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KMID : 1102220160350020114
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Kidney Research and Clinical Practice
2016 Volume.35 No. 2 p.114 ~ p.118
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Clinical significance of red blood cell distribution width in the prediction of mortality in patients on peritoneal dialysis
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Sun In-O
Chung Byung-Ha
Yoon Hyun-Ju
Kim Jeong-Ho
Choi Bum-Soon
Park Cheol-Whee
Kim Yong-Soo
Yang Chul-Woo
Lee Kwang-Young
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Abstract
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Background: In this study, we assessed whether red blood cell distribution width (RDW) was associated with all-cause mortality in patients on peritoneal dialysis (PD) and evaluated its prognostic value.
Methods: This study included 136 patients who had RDW levels at PD initiation from January 2007 to January 2014 at the Presbyterian Medical Center and Seoul St. Mary’s Hospital. We divided these patients into 2 groups (survivors vs. nonsurvivors), compared their clinical characteristics, and analyzed the predictors of survival.
Results: The study included 79 men and 57 women, with a mean age of 54?years (range, 15?85?years). The mean follow-up duration was 32?months (range, 1?80?months). Of 136 patients, 14 died during the follow-up period. When clinical characteristics of survivors (n?=?122) and nonsurvivors (n?=?14) were compared, no differences were identified, with the exception of serum albumin, total iron-binding capacity (TIBC), left ventricular ejection fraction, total leukocyte count, and RDW value. Survivors had higher serum albumin (3.4?±?0.5?vs. 3.0?±?0.5?g/dL, P?P?=?0.040) and lower TIBC (213.4?±?40.9 vs. 252.8?±?65.6, P?=?0.010), total leukocyte counts (6.9?×?103/μL vs. 8.6?×?103/μL, P?=?0.009), and serum RDW values (13.9?±?1.7 vs. 16.0?±?1.8, P?P?
Conclusion: RDW could be an additive predictor for all-cause mortality in patients on PD.
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KEYWORD
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Erythrocyte indices, Peritoneal dialysis, Red blood cell distribution width
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